Education
Bachelor of Arts May 2018
Department of Biology–Coe College
Doctor of Philosophy August 2024
Department of Pathology–Case Western Reserve University
Dissertation Title: O-GlcNAcylation and Response Prediction in Acute Myeloid Leukemia: A Data-Driven Approach
Mentors: Dr. David Wald and Dr. Tae Hyun Hwang
Research Experience
Higher Education Research Experience Fellow August 2017-December 2017
Molecular and Cellular Imaging Group–Oak Ridge National Lab, Oak Ridge, TN
Postdoctoral Scholar August 2024-current
Infectious Diseases–Case Western Reserve University, Cleveland, OH
Awards
Minority Scholar in Cancer Research Awardee AACR Annual Meeting 2022
Publications
Single Cell and Bulk RNA Expression Analyses Identifies Enhanced Hexosamine Biosynthetic Pathway and O-GlcNAcylation in Acute Myeloid Leukemia blasts and stem cells–Frontiers in Immunology 2024
Robert Schauner, Jordan Cress, Changjin Hong, David Wald, and Parameswaran Ramakrishnan
NK cells from COVID-19 positive patients exhibit enhanced cytotoxic activity upon NKG2A and KIR2DL1 blockade–Frontiers in Immunology 2023
Grace Lee, Robert Schauner, Juanita Burke, Jade Borocz, Smitha Vasana, Lukasz Sobieraj, Maria Giraudo, Zachary Jackson, Qasim Ansari, Maria Navas, Hany Sakr, and David Wald
Sequential Single-Cell Transcriptional and Protein Marker Profiling Reveals TIGIT as a Marker of CD19 CAR-T Cell Dysfunction in Patients with Non-Hodgkin Lymphoma–Cancer Discovery 2022
Zachary Jackson, Changjin Hong, Robert Schauner, Boro Dropulic, Paolo F. Caimi, Marcos de Lima, Maria Florencia Giraudo, Kalpana Gupta, Jane S. Reese, Tae Hyun Hwang, and David N. Wald
Single cell RNA sequencing of AML initiating cells reveals RNA-based evolution during disease progression–Leukemia 2021
L. C. Stetson, Dheepa Balasubramanian, Susan Pereira Ribeiro, Tammy Stefan, Kalpana Gupta, Xuan Xu, Slim Fourati, Anne Roe, Zachary Jackson, Robert Schauner, Ashish Sharma, Banumathi Tamilselvan, Samuel Li, Marcos de Lima, Tae Hyun Hwang, Robert Balderas, Yogen Saunthararajah, Jaroslaw Maciejewski, Thomas LaFramboise, Jill S. Barnholtz-Sloan, Rafick-Pierre Sekaly, and David N. Wald
Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma–Frontiers in Immunology 2020
Zachary Jackson, Anne Roe, Ashish Arunkumar Sharma, Filipa Blasco Tavares Pereira Lopes, Aarthi Talla, Sarah Kleinsorge-Block, Kayla Zamborsky, Jennifer Schiavone, Shivaprasad Manjappa, Robert Schauner, Grace Lee, Ruifu Liu, Paolo F. Caimi, Ying Xiong, Winfried Krueger, Andrew Worden, Mike Kadan, Dina Schneider, Rimas Orentas, Boro Dropulic, Rafick-Pierre Sekaly, Marcos de Lima, David N. Wald, and Jane S. Reese
Presentations
Transcriptional State Evolution in Pediatric Acute Myeloid Leukemia 2020
Biomedical Graduate Student Symposium
Discovering Biomarkers for Pediatric Acute Myeloid Leukemia using single-cell RNA sequencing 2021
ISMB/ECCB Annual Meeting
New platform for novel biomarker discovery using single-cell RNA sequencing on pediatric acute myeloid leukemia samples 2022
AACR Annual Meeting
Development of a Platform for Biomarker Discovery using scRNA sequencing on Pediatric AML Samples 2022
St. Jude Children’s Hospital Future Fellows Research Conference, Memphis, TN
Enhanced Hexosamine Biosynthetic Pathway and O-GlcNAcylation in Acute Myeloid Leukemia: A Data-Driven Approach 2024
Immunology Retreat, Case Western Reserve University
Skills
Computer Skills
Languages: R, Python
Linux, Mac, HPC
Seurat, tidyverse
git, SLURM
Snakemake, scverse
Affinity Creative Suite
Analysis Skills
Single-cell RNA seq
- Feature Barcoding
- Immune Repertoire
RNA seq
In silico flow cytometry
FlowJo
Laboratory Techniques
High-parameter Flow Cytometry
10x Genomics Library Preparation
Primary Cell Culture
DNA/RNA extraction
BSL-3 and BSL-2+ practices
Voulenteer/Non-profit work
Director of Media and Public Relations 2020-2023
Rise Up: Northeast Ohio, Cleveland, OH
Scientific Officer 2020-current
Rise Up: Northeast Ohio, Cleveland, OH
Memberships
American Association of Immunologists 2020-current
American Association for Cancer Research 2022-current
International Society for Computational Biology 2021-current